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Analytical validation of a direct competitive ELISA for multiple Mycotoxin detection in human serum

Mechanism Involving Nrf2-Keap1 Complex Mitigates the NLRP3 Inflammasome in PD In PD, the NLRP3 inflammasome acts as a central driver of neuroinflammation, perpetuating a self-sustaining inflammatory loop that accelerates the degeneration of dopaminergic neurons

[DOI] [PubMed] [Google Scholar] 14.Chronopoulou R, Xylouri E, Fegeros K, Politis I

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Unlike animals, humans cannot synthesize vitamin C on our own

The presence of an expanded polyQ tract in proteins leads to a self-association that competes with polyQ-mediated interaction with beclin-1 and impairs autophagy in vitro (as observed for ATXN3) and in vivo (as observed for huntingtin), at least in conditions of starvation [85]